Takaitaccen Bayani:
Lambar CAS: 69004-03-1
Tsarin kwayoyin halitta: C18H14F3N3O4S
Nauyin kwayoyin: 425.38
Tsarin sinadarai:
| Bayanan asali | |
| Sunan samfur | Toltrazuril |
| CAS No. | 69004-03-1 |
| Launi | Fari ko kusan fari crystalline foda |
| Daraja | Matsayin Ciyarwa |
| Adana | Rufewa a bushe, Zazzabin ɗaki |
| Rayuwar Rayuwa | shekaru 2 |
| Amfani | Shanu, Kaza, Kare, Kifi, Doki, Alade |
| Kunshin | 25kg/ganga |
Bayani
Toltrazuril (Baycox®, Procox®) maganin triazinon ne wanda ke da faffadan anticoccidial da antiprotozoalactivity. Ba a samunsa ta kasuwanci a Amurka, amma ana samunsa a wasu ƙasashe. Yana aiki da matakan asexual da jima'i na coccidia ta hanyar hana rarraba makaman nukiliya na schizonts da microga-mons da jikin bango na macrogamont. Yana iya zama da amfani a cikin maganin porcinecoccidiosis na jarirai, EPM, da hepatozoonosis na canine.
Toltrazuril da manyan metabolite ponazuril (toltrazuril sulfone, Marquis) sune magungunan antiprotozoal na tushen triazine waɗanda ke da takamaiman aiki akan cututtukan coccidial apicomplexan. Babu Toltrazuril a cikin Amurka.
Aikace-aikacen samfur
Alade: An nuna Toltrazuril don rage alamun coccidiosis a cikin aladu masu shayarwa da suka kamu da cutar yayin da aka ba da 20-30 mg / kg BWdose guda ɗaya zuwa 3 zuwa 6-dayold alade (Driesen et al., 1995). An rage alamun asibiti daga 71 zuwa 22% na aladu masu shayarwa, kuma zawo da kuma fitar da oocyst an rage su ta hanyar maganin baki daya. Kayayyakin da aka yarda suna ɗaukar lokacin janyewar kwanaki 77 a cikin Burtaniya.
Calves da raguna: Ana amfani da Toltrazuril don rigakafin alamun asibiti na coccidiosis da rage zubar da coccidia a cikin maraƙi da raguna a matsayin magani guda ɗaya. Lokutan janyewa a Burtaniya kwanaki 63 ne da 42 na maraƙi da raguna, bi da bi.
Karnuka: Don hepatozoonosis, toltrazuril ana ba da baki a 5 mg/kg BW kowane awanni 12 na kwanaki 5 ko kuma a ba da baki a 10 mg/kg BW kowane awanni 12 na tsawon kwanaki 10 ya haifar da gafarar alamun asibiti a cikin karnuka masu kamuwa da cuta a cikin kwanaki 2-3. Macintire et al., 2001). Abin takaici, yawancin karnukan da aka yi wa magani sun sake dawowa kuma a ƙarshe sun mutu daga hepatozoonosis. A cikin kwikwiyo tare da Isospora sp. kamuwa da cuta, jiyya tare da 0.45 MG emodepside a hade tare da 9 MG / kg BW toltrazuril (Procox®, Bayer Animal Health) yana rage adadin oocyst na fecal da 91.5-100%. Babu bambanci a cikin tsawon lokacin zawo lokacin da aka fara magani bayan farawar alamun asibiti a lokacin kamuwa da cuta (Altreuther et al., 2011).
Cats: A cikin kittens da aka gwada gwaji tare da Isospora spp., Jiyya tare da kashi ɗaya na baki na 0.9 MG emodepside a hade tare da 18 mg / kg BW toltrazuril (Procox®, Bayer AnimalHealth) yana rage zubar da oocyst ta 96.7-100% idan an ba shi a lokacin prepatent. lokaci (Petry et al., 2011).
Dawakai: An kuma yi amfani da Toltrazuril don maganin EPM. Wannan magani yana da lafiya, har ma a manyan allurai. Maganin da aka ba da shawarar na yanzu shine 5-10 mg/kg na baki na kwanaki 28. Duk da ingantaccen inganci tare da toltrazuril, amfani da shi ya ragu a cikin dawakai saboda mafi kyawun samun sauran magunguna masu inganci.
