Takaitaccen Bayani:
Lambar CAS: 70288-86-7
Tsarin kwayoyin halitta: C48H74O14
Nauyin kwayoyin: 875.09
Tsarin sinadarai:
| Bayanan asali | |
| Sunan samfur | Ivermectin |
| Daraja | Matsayin Magunguna |
| Bayyanar | Farin foda |
| Assay | 99% |
| Rayuwar rayuwa | shekaru 2 |
| Shiryawa | 25kg/ kartani |
| Sharadi | Wuri mai sanyi |
Bayanin Ivermectin
Ivermectin wani maganin antiparasitic ne mai tasiri a cikin maganin onchocerciasis, ko "makanta kogi". Tun da ivermectin yana aiki don hana tsutsa mai girma daga samar da microfilariae, yana buƙatar gudanar da shi sau ɗaya ko sau biyu a shekara.
Tasirin Ivermectin
Ivermectin fari ne ko haske rawaya crystalline foda kuma mai narkewa a cikin methyl barasa, ester da aromatic hydrocarbon amma ruwa. Ivermectin wani nau'i ne na maganin rigakafi wanda ke da tasirin tuki da kisa akan nematodes, kwari da mites. Allura da troche da ake yi daga ivermectin ana amfani da su ne a cikin maganin nematode na ciki na dabbobi, hypodermosis na dabba, tsutsa gardama, tsummokin tumaki na hanci gardama, da ciwon tumaki da aladu. Bayan haka, ivermectin kuma ana iya samuwa don maganin nematodes-parasitic nematodes (ascarid, lungworm) a cikin kaji. Bugu da kari, ana iya sanya ta ta zama maganin kwari na noma don kashe mite, plutella xylostella, caterpillar kabeji, ma'adinan ganye, phylloxera da nematode wadanda suke da yawa a cikin tsirrai. Babban fasalin wannan maganin kwari shine cewa yana da ƙananan illolin kuma yana iya tuƙi da kashe nau'ikan ƙwayoyin cuta iri-iri na ciki da waje a lokaci guda.
Pharmacology na Ivermectin
Ivermectin na cikin nau'in abubuwan da aka sani da avermectines. Waɗannan su ne lactones macrocylic da aka samar ta hanyar fermentation na actinomycete, Streptomyces avermitilis. Ivermectin wani babban bakan wakili ne mai aiki da nematodes da arthropods a cikin dabbobin gida kuma ana amfani dashi sosai a cikin likitan dabbobi.[1]. An fara gabatar da maganin a cikin mutum a cikin 1981. An nuna cewa yana da tasiri a kan nau'in nematodes kamar Strongyloides sp., Trichuris trichiura, Enterobius vermicularis, Ascaris lumbricoides, tsutsotsi tsutsotsi da Wuchereria bancrofti. Duk da haka, ba shi da wani tasiri a kan ciwon hanta da kuma cestodes[2].
