Bayanan asali | |
Sunan samfur | Amprolium hydrochloride |
Daraja | Matsayin ciyarwa |
Bayyanar | Farin Crystalline foda |
Assay | 99% |
Rayuwar rayuwa | Shekaru 2 |
Shiryawa | 25kg/drum |
Sharadi | Ajiye a wuri mai sanyi, bushe, duhu a cikin akwati da aka rufe sosai ko silinda. |
Gabatarwar Amprolium Hydrochloride
Amprolium shine analog na thiamine da kuma wakili na antiprotozoal wanda ke tsoma baki tare da metabolism na thiamine kuma yana hana haɗin carbohydrate. Yana da gasa yana hana shan thiamine ta hanyar E. tenella schizonts da ta ƙwayoyin hanji mai masaukin kaji (Kis = 7.6 da 326 μM, bi da bi). Hakanan yana hana samuwar hexose da amfani da pentose ex vivo a cikin keɓaɓɓen erythrocytes na bera da ke cikin hanta, koda, zuciya, da nama na hanji suna bin tsarin abinci. Amprolium (1,000 ppm a cikin ciyarwa) yana hana fitowar oocyst da sporulation na Eimeria maxima, E. bruneti, da E. acervulina a cikin kajin da suka kamu da cutar. Hakanan yana rage rauni da maki oocyst da mace-mace na E. Tenella da ke kamuwa da kajin bayan gudanar da abinci na kashi 125 ppm. Amprolium (100 μM) yana haifar da apoptosis a cikin sel adrenal na bera na PC12 kuma yana ƙara matakin fashewar caspase-3. An yi amfani da abubuwan da ke ɗauke da amprolium azaman coccidiostats wajen sarrafa kaji.
Amfani da Amprolium Hydrochloride
Amprolium Hydrochloride yana da kyakkyawan aiki akan Eimeria tenella da E. acervulina a cikin kaji kuma ana iya amfani dashi azaman maganin warkewa ga waɗannan kwayoyin halitta. Yana da aiki na gefe ko raunin aiki akan E. maxima, E. mivati, E. necatrix, ko E. bruneti. Ana amfani da shi sau da yawa tare da wasu wakilai (misali, ethopabate) don inganta iko akan waɗannan kwayoyin halitta.
A cikin shanu, amprolium yana da izini don magani da rigakafin E. bovis da E. zurnii a cikin shanu da maruƙa.
An yi amfani da Amprolium a cikin karnuka, alade, tumaki, da awaki don sarrafa coccidiosis, kodayake babu samfuran da aka yarda da su a cikin Amurka don waɗannan nau'ikan.