Takaitaccen Bayani:
Lambar CAS: 1197-18-8
Tsarin kwayoyin halitta: C8H15NO2
Nauyin kwayoyin: 157.21
Tsarin sinadaran:
| Bayanan asali | |
| Sunan samfur | Tranexamic acid |
| Daraja | Matsayin kwaskwarima |
| Bayyanar | Fari ko kusan fari, lu'ulu'u foda |
| Assay | 99% |
| Rayuwar rayuwa | shekaru 2 |
| Shiryawa | 25kg/drum |
| Abubuwan Sinadarai | Yana iya narkewa cikin ruwa kuma a cikin glacial acetic acid kuma yana da ɗan narkewa sosai a cikin ethanol kuma kusan ba zai iya narkewa a cikin ether. |
Bayani
Tranexamic acid wani nau'in aminomethylbenzoic acid ne, kuma wani nau'in magungunan antifibrinolytic don dakatar da zubar jini. Tsarin hemostasis na tranexamic acid yayi kama da aminocaproic acid da aminomethylbenzoic acid, amma tasirin ya fi karfi. Ƙarfin shine sau 7 zuwa 10 na aminocaproic acid, sau 2 na aminomethylbenzoic acid, amma guba yana kama da haka.
Tsarin sinadarai na tranexamic acid yayi kama da lysine, gasa na hana plasmin asali a cikin adsorption na fibrin, don hana kunna su, sunadaran fiber na kariya kar su lalace ta hanyar plasmin kuma su narke, a ƙarshe sun sami hemostasis. Ana amfani da shi a cikin jiyya na m ko na kullum, na gida ko na tsarin fibrinolytic hyperthyroidism na jini wanda ya haifar da zub da jini, irin su zubar da jini na haihuwa, zubar da jini na koda, zubar da jini na hypertrophy na prostate, hemophilia, tarin fuka hemoptysis, zubar da ciki, bayan aiki na hanta, huhu. , saifa da sauran viscera hemorrhage; Hakanan za'a iya amfani dashi a tiyata lokacin da zubar jini mara kyau da sauransu.
Tranexamic acid na asibiti yana da tasiri sosai ga cututtukan cizon kwari, dermatitis da eczema, purpura mai sauƙi, urticaria na yau da kullun, urticaria na jima'i na wucin gadi, fashewa mai guba da fashewa. Kuma yana da wani tasiri akan erythroderma, scleroderma, lupus erythematosus (SLE), Erythema multiforme, shingles da alopecia areata. Maganin tasirin angioedema na gado shima yana da kyau. A cikin maganin Chloasma, magani na gabaɗaya yana aiki kusan makonni 3, yana da tasiri sosai makonni 5, hanya na kwanaki 60. An ba da baki a cikin allurai na 0.25 ~ 0.5 g, a rana sau 3 ~ 4. Wasu marasa lafiya na iya zama tashin zuciya, gajiya, raɗaɗi, rashin jin daɗi na ciki, da kuma illar gudawa bayan alamun ja da baya.
Alamomi
Jini daban-daban da ke haifar da m ko na yau da kullun, na gida ko na tsarin farko na hyperfibrinolysis; na biyu hyperfibrinolytic jihar lalacewa ta hanyar yada intravascular coagulation. Gabaɗaya kar a yi amfani da wannan samfurin kafin heparinization.
Jini ko zubar da jini na tiyata a cikin nama da gabobin da ke da yawan masu kunna plasminogen kamar su prostate, urethra, huhu, kwakwalwa, mahaifa, glandan adrenal, da thyroid.
Mai adawa da ƙwayar plasminogen activator (t-PA), streptokinase, da urokinase.
Fibrinolytic hemorrhage wanda ke haifar da zubar da ciki na wucin gadi, raguwar wuri na farko, haihuwar mutuwa da zubar da ruwa na amniotic; da kuma ƙãra menorrhagia lalacewa ta hanyar pathological intrauterine fibrinolysis.
Cerebral neuropathy m zub da jini, kamar subarachnoid hemorrhage da intracranial aneurysm hemorrhage, sakamakon Amstat a cikin wannan yanayin ya fi na sauran anti-fibrinolytic jamiái. Dole ne a biya kulawa ta musamman ga haɗarin edema na cerebral ko raunin kwakwalwa.Ga marasa lafiya masu tsanani tare da alamun tiyata, wannan samfurin za'a iya amfani dashi kawai azaman magani na adjuvant.
Don maganin edema na angioneurotic na gado, zai iya rage adadin da tsanani na lokuta.
An yi amfani da shi a cikin marasa lafiya tare da hemophilia don aikin zubar da jini a hade tare da wasu kwayoyi.
Marasa lafiyar Hemophilia masu raunin Factor VIII ko Factor IX a cirewar haƙora ko tiyatar baki idan an yi aikin jini.
