Takaitaccen Bayani:
Lambar CAS:51322-75-9
Tsarin kwayoyin halitta:C9H8ClN5S
nauyin kwayoyin:253.71
Tsarin sinadarai:
| Bayanan asali | |
| Sunan samfur | Tizanidine |
| Daraja | Babban darajar Pharma |
| Bayyanar | Farin Foda |
| Assay | 99% |
| Rayuwar rayuwa | shekaru 2 |
| Shiryawa | 25kg/drum |
| Sharadi | Adana a -20°C |
Shaci
Tizanidine shine imidazoline guda biyu na nitrogen heterocyclic penene. Tsarin yana kama da na clonidine. A cikin 1987, an fara jera shi a cikin Finland azaman tsakiyar adrenalin α2 agonist mai karɓa. A halin yanzu, ana amfani dashi azaman shakatawa na tsoka na tsakiya a asibiti. Ana iya amfani da shi don magance ciwon tsoka mai raɗaɗi, irin su ciwon wuyan wuyansa da torticollis. Hakanan za'a iya amfani da shi don magance ciwon bayan tiyata, kamar ƙwayar diski da ciwon gwiwa. Ya fito ne daga ankylosis na cututtukan jijiyoyin jiki, irin su sclerosis mai yawa, myelopathy na yau da kullun, haɗarin cerebrovascular da sauransu.
Aiki
Ana amfani da shi don rage tashin hankali na skeletal, tsoka spasm da myotonia lalacewa ta hanyar kwakwalwa da kashin baya rauni, cerebral hemorrhage, encephalitis da mahara sclerosis.
Ilimin harhada magunguna
Yana zaɓan yana rage sakin amino acid mai ban sha'awa daga interneurons kuma yana hana tsarin synaptic da yawa da ke da alaƙa da wuce gona da iri. Wannan samfurin baya shafar watsa neuromuscular. An yarda da shi da kyau. Yana da tasiri ga m tsoka spasms mai raɗaɗi da na kullum ankylosis ya samo asali daga kashin baya da kuma kwakwalwa. Zai iya rage juriya na motsin motsi, rage spasticity da clonus, da kuma ƙara ƙarfin motsi na son rai.
Amfani
Labeled Tizanidine, wanda aka yi niyya don amfani azaman ma'auni na ciki don ƙididdige Tizanidine ta GC- ko LC-mass spectrometry. Tizanidine na iya samun amfani da magani azaman mai hana SARS-CoV-2 babban mai hanawa.
Amfanin asibiti
Tizanidine shine mai karɓar mai karɓa na adrenergic α2 na tsakiya wanda ake amfani dashi don kula da yanayin spasticity na tsoka, irin su sclerosis da yawa.
Hanyar aiki
Tizanidine analog ne mai sassaucin ra'ayi na tsakiya mai aiki na clonidine wanda aka yarda don amfani da shi don rage spasticity da ke hade da ƙwayar cuta ko rauni na kashin baya. Hanyoyin aikin sa don rage spasticity yana nuna presynaptic hanawa na ƙananan ƙwayoyin mota a cikinα2-adrenergic receptor sites, rage saki na excitatory amino acids da kuma hana gudanarwa ceruleospinal hanyoyin, don haka haifar da raguwa a spasticity. Tizanidine kawai yana da ɗan ƙaramin juzu'i na aikin antihypertensive na clonidine, mai yiwuwa saboda aikin da aka zaɓa a cikin rukuni na zaɓi.α2C-adrenoceptors, wanda ya bayyana yana da alhakin aikin analgesic da antispasmodic. imidazolineα2-masu jijiyoyi (20).
