Takaitaccen Bayani:
Lambar CAS: 1405-10-3
Tsarin kwayoyin halitta: C23H48N6O17S
Nauyin kwayoyin halitta: 712.72
Tsarin sinadaran:
| Bayanan asali | |
| Sunan samfur | Neomycin sulfate |
| CAS No. | 1405-10-3 |
| Bayyanar | Fari zuwa Foda Jawo Kadan |
| Daraja | Babban darajar Pharma |
| Ruwan Solubility | Mai narkewa cikin ruwa |
| Adana | 2-8 ° C |
| Rayuwar Rayuwa | 2 Ykunnuwa |
| Kunshin | 25kg/Drum |
Bayanin Samfura
Neomycin sulfate shine maganin rigakafi na aminoglycoside da mai hana furotin tashar calcium. Neomycin sulfate kuma yana ɗaure zuwa prokaryotic ribosomes yana hana fassarar kuma yana da tasiri akan ƙwayoyin gram-tabbatacce da gram-korau. Neomycin sulfate yana hana PLC (Phospholipase C) ta hanyar ɗaure zuwa inositol phospholipids. Hakanan yana hana ayyukan phosphatidylcholine-PLD kuma yana haifar da motsin Ca2 + da kunna PLA2 a cikin platelet ɗin ɗan adam. Neomycin sulfate yana hana DNAse I jawo lalatawar DNA. Ana amfani da shi don rigakafi ko magance cututtukan fata da ƙwayoyin cuta ke haifarwa. Ba shi da tasiri a kan cututtukan fungal ko ƙwayoyin cuta.
Aikace-aikace
Neomycin sulfate wani maganin rigakafi ne na aminoglycoside wanda S. fradiae ya samar wanda ke hana fassarar furotin ta hanyar ɗaure zuwa ƙaramin yanki na prokaryotic ribosomes. Yana toshe tashoshi Ca2+ masu ƙarfin wutar lantarki kuma shine mai hanawa mai ƙarfi na tsokar kwarangwal sarcoplasmic reticulum Ca2+ sakin. An nuna NEOMYCIN SULFATE don hana inositol phospholipid juyawa, phospholipase C, da phosphatidylcholine-phospholipase D aiki (IC50 = 65 μM). Yana da matukar tasiri a kan kwayoyin cutar Gram-positive da Gram-korau kuma ana amfani da shi sosai don rigakafin gurɓatar ƙwayoyin cuta na al'adun tantanin halitta.
