Takaitaccen Bayani:
Lambar CAS:24729-96-2
Tsarin kwayoyin halitta:C18H34ClN2O8PS
Nauyin kwayoyin: 504.96
Tsarin sinadarai:
| Bayanan asali | |
| Sunan samfur | Clindamycin Phosphate |
| Daraja | Babban darajar Pharma |
| Bayyanar | farin foda |
| Assay | 95% |
| Rayuwar rayuwa | shekaru 2 |
| Shiryawa | 25kg/drum |
| Sharadi | Barga, amma adana sanyi. Ba tare da jituwa tare da magungunan oxidizing mai ƙarfi, alli gluconate, barbiturates, magnesium sulfate, phenytoin, bitamin na rukunin B na sodium. |
Bayani
Clindamycin phosphate shine ester mai narkewa da ruwa na maganin rigakafi na semisynthetic wanda 7 (S) - chloro-musanya na rukunin 7 (R) -hydroxyl na maganin rigakafi na iyaye, lincomycin. Ya fito ne daga lincomycin (lincosamide). Yana da farko bacteriostatic mataki a kan Gram-tabbatacce aerobes da kuma fadi da kewayon anaerobicbacteria. Yana da maganin rigakafi da ake amfani da shi wajen maganin cututtuka. Wadannan na iya haɗawa da cututtuka na fili na numfashi, septicaemia, peritonitis da cututtuka na kashi. Ana kuma amfani da ita don magance matsananciyar kurajen fuska.
Amfani
Ana amfani da Clindamycin phosphate a kai a kai shi kaɗai ko a haɗin gwiwa tare da benzoyl peroxide a cikin maganin kumburin kurajen vulgaris. A cikin yin la'akari da yuwuwar fa'idodin maganin clindamycin na Topical, yakamata a yi la'akari da yiwuwar mummunan tasirin GI mai alaƙa da maganin. Dole ne a keɓance magungunan kuraje vulgaris kuma a sake gyara su akai-akai dangane da nau'ikan raunukan kurajen da suka fi yawa da kuma martanin jiyya. Maganganun cututtuka na Topical, gami da clindamycin, gabaɗaya suna da tasiri a cikin maganin kuraje masu laushi zuwa matsakaici. Duk da haka, yin amfani da magungunan kashe kwayoyin cuta kamar yadda monotherapy zai iya haifar da juriya na kwayan cuta; Wannan juriya yana da alaƙa da raguwar ingancin asibiti.Topical clindamycin yana da amfani musamman idan aka yi amfani da shi tare da benzoyl peroxide ko abubuwan retinoids. Sakamako na binciken asibiti ya nuna cewa haɗin gwiwa yana haifar da raguwa a cikin jimlar raunuka na 50-70%.
Clindamycin 2-phosphate shine aa gishiri na clincamycin, lincosamide Semi-synthetic. Ana shirya gishiri ta hanyar zaɓin phosphorylation na 2-hydroxy moiety na sukari na clindamycin. Gabatar da fosfat ɗin yana ba da ingantaccen narkewa don abubuwan allura. Kamar sauran membobi na dangin lincosamide, clindamycin 2-phosphate babban maganin rigakafi ne mai fa'ida tare da aiki akan ƙwayoyin cuta anaerobic da protozoans. Clindamycin yana aiki ta hanyar ɗaure zuwa 23S ribosomal subunit, yana toshe haɗin furotin.
