Takaitaccen Bayani:
Lambar CAS: 27164-46-1
Tsarin kwayoyin halitta: C14H15N8NaO4S3
Nauyin kwayoyin: 478.5
Tsarin sinadarai:
| Bayanan asali | |
| Sunan samfur | Cefazolin sodium gishiri |
| CAS No. | 27164-46-1 |
| Bayyanar | Fari zuwa Kashe-Farin crystalline foda |
| Daraja | Babban darajar Pharma |
| Adana | Ajiye a wuri mai duhu, yanayi mara kyau, 2-8 ° C |
| Rayuwar Rayuwa | shekaru 2 |
| Kwanciyar hankali | Barga, amma yana iya zama mai kula da zafi - adana cikin yanayi mai sanyi. Zai iya canza launin bayan fallasa zuwa haske - adana a cikin duhu. Wanda bai dace ba tare da magunguna masu ƙarfi masu ƙarfi. |
| Kunshin | 25kg/Drum |
Bayanin Samfura
Kwayoyin rigakafi na wucin gadi wanda ke dauke da cephalosporins a cikin kwayoyin cephalosporins. An fassara shi da Xianfeng mycin. na β-Lactam maganin rigakafi, ee β- Abubuwan da aka samo na 7-aminocephalosporanic acid (7-ACA) a cikin maganin rigakafi na lactam suna da irin wannan tsarin kwayoyin cuta. Irin wannan magani na iya lalata bangon tantanin halitta kuma ya kashe su yayin lokacin haihuwa. Yana da tasirin zaɓi mai ƙarfi akan ƙwayoyin cuta kuma kusan babu guba ga ɗan adam, tare da fa'idodi irin su bakan ƙwayoyin cuta mai faɗi, tasirin ƙwayoyin cuta mai ƙarfi, juriya ga enzymes penicillin, da ƙarancin rashin lafiyar idan aka kwatanta da penicillin. Don haka yana da mahimmancin ƙwayoyin cuta tare da babban inganci, ƙarancin guba, da aikace-aikacen asibiti mai faɗi. An haɓaka ƙarni na farko cephalosporins a baya, tare da aikin kashe ƙwayoyin cuta masu ƙarfi idan aka kwatanta da Chemicalbook, kunkuntar ƙwayoyin cuta, da mafi kyawun tasirin ƙwayoyin cuta na Gram fiye da ƙwayoyin cuta na Gram. Samar da Staphylococcus aureus β-Lactamase yana da kwanciyar hankali kuma yana iya hana samar da ƙwayoyin cuta mara kyau β-Lactamases ba su da ƙarfi kuma har yanzu ana iya samar da su ta yawancin ƙwayoyin cuta na Gram β- Lactamases sun lalace. Cefazolin sodium shine cephalosporin ƙarni na farko na roba wanda ke da tasirin kashe kwayoyin cuta akan ƙwayoyin gram-tabbatacce da gram-korau. An fi amfani da shi a cikin cututtuka na tsarin numfashi, tsarin urogenital, nama mai laushi na fata, kashi da haɗin gwiwa, da biliary tract da ke haifar da ƙwayoyin cuta masu mahimmanci, da kuma endocarditis, sepsis, pharyngeal da ciwon kunne. Yana da aiki mai ƙarfi akan ƙwayoyin ƙwayoyin gram-tabbatacce irin su Staphylococcus aureus da Streptococcus (ban da Enterococcus), kuma ya fi cephalosporins na ƙarni na uku.
Amfanin Sinadari
Cefazolin (Ancef, Kefzol) yana daya daga cikin jerin semisyntheticcephalosporins wanda aikin C-3 acetoxy ya maye gurbinsa ta hanyar heterocycle mai dauke da thiol-a nan, 5-methyl-2-thio-1,3,4-thiadiazole. Hakanan ya ƙunshi ƙungiyar tetrazolylacetyl acylating na ɗan lokaci. Cefazolin an sake shi a cikin 1973 azaman gishiri sodium mai narkewa da ruwa. Yana aiki ne kawai ta hanyar kulawar iyaye.
Cefazolin yana samar da matakan jini mafi girma, jinkirin renalclearance, da tsawon rabin rayuwa fiye da sauran ƙarni na farko-cephalosporins. Yana da kusan kashi 75% na furotin da ke daure inplasma, ƙimar mafi girma fiye da sauran cephalosporins. Tun da farko a cikin vitro da nazarin asibiti sun nuna cewa cefazolin ya fi aiki da gram-negative bacilli amma ba ya da tasiri a kan Gram-positive cocci fiye da ko dai cephalothin ko cephaloridine. Yawan faruwa na thrombophlebitis bayan allura ta ciki da jin zafi a wurin allurar intramuscularly sun bayyana a matsayin mafi ƙanƙanta na parenteralcephalosporins.
